What laboratory result would indicate reduced renal status in a patient who experienced a major burn?

A reduced glomerular filtration rate (GFR) is indicative of impaired kidney function, which is particularly relevant in the context of a major burn injury. In severe burns, the body experiences significant volume loss and alterations in blood flow, which can lead to acute kidney injury. The kidneys filter waste products from the blood, and as their function declines, the GFR decreases. This reduced GFR reflects the kidneys' decreased ability to clear waste effectively, resulting in the accumulation of waste products in the blood.

In burn patients, factors such as shock, dehydration, and direct tissue damage can contribute to renal compromise, making the assessment of GFR vital for monitoring renal status. An elevated GFR would suggest adequate kidney function, while decreased levels would signify potential renal impairment. Thus, a reduced GFR is a critical indicator of declining renal status in the aftermath of a major burn, highlighting the kidneys' compromised ability to filter blood effectively.