In a patient experiencing a severe burn, what will be the renal response in the first 24 hours?

In the first 24 hours following a severe burn, the renal response is typically characterized by a decrease in the glomerular filtration rate (GFR). This reduction is primarily due to several physiological factors associated with burn injury, including hypovolemia, shock, and decreased renal perfusion.

When a person experiences a severe burn, there is significant fluid loss due to evaporation and injury, leading to reduced circulating blood volume. The body responds to this hypovolemic state by triggering compensatory mechanisms such as vasoconstriction and the release of hormones like renin, resulting in a decrease in renal blood flow and, consequently, a lower GFR.

Additionally, with the decrease in GFR, urine output typically decreases as well, as the kidneys conserve fluid in response to perceived dehydration. While there may also be a rise in blood urea nitrogen (BUN) due to tissue breakdown and dehydration, the GFR is the key renal response that signifies the acute phase following severe burns.

Understanding the renal response during this critical period is crucial for managing the patient's fluid resuscitation and monitoring renal function effectively. Recognizing that a decreased GFR indicates the kidneys' response to stressors allows healthcare professionals to intervene appropriately and prevent further